ABSTRACT
All at the Faculty of Medicne, Khon Kaen Univerisity Accident has been the leading cause of death in Thailand since AD 1976. Alcohol drinking has been strictly prohibited for the driver in many of the developed country. This study was conducted at accident and emergency ward of Srinagarind hospital. The traffic accident patients with suspicious of drinking were interiewed and their blood was drawn for alcohol level using gas chromatographic head space analysis. There were 68 percents of 183 suspected drunk accident cases. Those who had the high level of alcohol of 1.50-4.00 Promil which identified as drunk were found as many as 32 percents with one case over 4.00 Promil. Most of the accident occurred in the teenagers. Weekends and the time between 19.00 pm. to 24. pm. were the most liable period for accident.
ABSTRACT
Background : Conservation laryngectomy is an alternative for organ preservation treatment of early laryngeal cancer beside radiotherapy with a comparable oncological result. However, result of this treatment option in Srinagarind Hospital has never been reported.Objective : To study the result of conservation laryngec tomy in both oncologic and functional aspectDesign : Retrospective, descriptive studySetting : Patients who diagnosed as laryngeal cancer and underwent conservation laryngectomyIntervention : Conservation larygectomyMeasurements : Recurrent rate or cure rate and laryngeal function (deglutition without aspiration, respiration and phonation)Results : There are 9 cases in 10 year period underwent vertical hemilaryngectomy, supraglottic laryngectomy and supracricoid laryngectomy 3 cases each. There is only one case who underwent supraglottic laryngectomy had recurrence at primary site and one case of stage III cancer and underwent supracricoid laryngectomy had recurrence at primary site and one case of stage III cancer and underwent supracricoid laryngectomy died from lung metastasis. All cases can be preserved all functions of larynx including deglutition without aspiration, normal nasal breathing without tracheotomy tuge and communicable voice.Conclusions : Conservation laryngectomy is a considerable option for laryngeal preservation in treatment of laryngeal cancer beside radiotherapy.
ABSTRACT
Background : laryngeal cancer is the common cancer in ENT practice. According to tumor registry of Srinagarind Hospital, it is the third most common cancer of upper G-I \& Respiratory tract cancer being after oral and nasopharyngeal cancer. Additionally it had never been reported in Srinagarind Hospital.Objective : Study about character of laryngeal cancer and its treatmentDesign : Retrospective, descriptive studySetting : Srinagarind Hospital, Khon Kaen University Subject : Patients whose diagnosed as squamous cell carcinoma of the larynx and were treated in srinagarind Hospital since 1993-1997.Results : There were 59 cases included in this study. Fifty-eight cases were male and average age was 63 years old. The most common type was supraglottic cancer (44%) following by glottic cancer (31%) and most cases 76%) were advanced cases, most (55%) were treated by surgery with postoperative radiation following by primary radiation (32%). Three of nine cases whom received neck dissection have positive malignancy in neck node specimen.Summary : Most of laryngeal cancers were advanced stage that need a combined treatment (surgery with postoperative radiation) as the most common treatment option.
ABSTRACT
Background : The infraorbital nerve is one of the branches of the maxillary division of the trigeminal nerve. It lies in the infraorbital canal forming the roof of maxillary sinus. The infraorbital canal dehiscence may have a cance to disturb the infraorbital nerve more than the non-dehiscence and could be a cause of the facial pain. Many investigators have been reported the prevalence of the infraorbital canal dehiscence in many countries but not in Thailand. The purpose of this investigation is to study the prevalence of infraorbital canal dehiscence and decribe the morphology of the infraorbital canal in Thai cadavers.Objective : To study the prevalence of the infraorbital canal dehiscance in Thai cadaveric skull and described the morphology of the i infraorbital canal in Thai cadavers.Design : A descriptive study.Setting : The study was carried out at the Department of Anatomy and the Department of Otolaryngology, Faculty of Medicine, Khon Kaen University, Kkhon Kaen, Thailand.Subjects : The study included 80 specimens of half head and face from formalin-embalmed cadavers, 36-84 years of age (average 62 years(. They could be indentified for genders by only 62 specimens; male 9 specimens and female 13 specimens.Setting : 1. To study the infraorbital canal dehiscence that convering the infraorbital nerve as the following aspects :1.1 The number of the sample that found dehiscence, comparing male to female as well as right to left sides1.2 The site of the wall of the infraorbital canal which occurred dehiscence.1.3 To measure the width and the length of dehiscence of the infraorbital canal.2. To observe the type of infraorbital canal which occupied infraorbital nerve and measure the depth of the canal on the roof of the maxillary sinus.3. To study the dehiscence of the bone that covers the superior alveolar nerve which gives the branch to supply the upper teeth as the following as pects :3.1 The number of the sample with dehiscence.3.2 The site of the wall of the canal that found dehiscence.3.3 To measure the width and the length of dehiscence.4. To measure the length between infraorbital foramen and infraorbital rim.5. To study the number of the sample that dehiscence bone occxured around both infraorbital and superior alveolar nerves.Results: 1. Infraorbital canal dehiscence1.1 The infraorbital canal dehiscence was found in 15 specimens from 79 specimens of samples (1 specimen was broken before study). The sex difference and dehiscence was 7 specimens out of 61 in male and 4 out of 61 specimens in female from 61 specimens that can identify the sex. In aspect of the side, we found that dehiscence in the right side was 7 specimens and the left side was 8 specimens.1.2 The number of the side of the wall of infraorbital canal dehiscence at the inferior, lateral, medial, infraorbital and infraorbital wall were 5,4,3,2 and 1 out of 15 specimens respectively.1.3 The width of dehiscence of infraorbital canal was 0.5-3.5 mm., means 1.45 mm. The ratio on the width of infraorbital canal and the diameter of infraorbital nerve was 10-100%, means 48%. The length of the infraorbital canal dehiscence was 2.0-11.0 mm., means 5.09 mm.2. The number of three types of infraorbital canal dehiscence were 1, 5 and 9 specimens of the first, secon and third type respectively, whereas the non-dehiscence were 12, 26 and 26 sfpecimens respectively. Moreover the depth of the canal on the roof of maxillary sinus was 0 mm., 2.0-8.0 mm. (mean 4.6), and 3.5-12 mm. (mean 6.9) of the first, second and third type respectively.3. Superior alveolar nerve dehiscence3.1 The superior alveolar nerve dehiscence was found 36 specimens out of 79 specimens.3.2 The number of the site of the wall of superior alveolar nerve dehiscence at the lateral, inferior, medial anterior, infraorbital and inferomedial wall were 13, 9, 4, 3, 1 and 1 specimes respectively.3.3 The width of dehiscence of superior alveolar nerve was 0.5-2.5 mm., mean 1.29 mm. The ratio on the width of the bone cover the superior alveolar nerve and the diameter of superior alveolar nerve was 40-100 %, means 96%. The length of the dehiscence was 1.0-14.0 mm., mean 5.97 mm.4. The distance from infraorbital foramen to the infraorbital rim of the orbit was 5.5-11.0 mm., mean 8.27 mm. Indehiscence group of the infraorbital canal and 1.0-11.0 mm., mean 7.49 mm. In non-dehiscence group.5. Only one specimen of maxillary sinus that was found with dehiscence covering both infraorbital and superior alveolar nerve.Conclusions : The results of this observation is the basic knowledge of the prevalence of the infraorbital canal dehiscence in Thai cadavers. The infraorbital canal dehiscence was found 15 out of 79 of cases. The dehiscence was found in femal more than male but there was no significance difference between right and left sides. Among the types of infraorbital canal, the most prevalence was type 3 (total prominence type)j. The knowledge from this observation is useful in medical sciences such as help to explain in diagnosis of the cause of facial pain. One must be careful in performing antrostomy of the maxillary sinus.Key words : Dehiscence, infraorbital canal, infraorbital foramen, infraorbital nerve
ABSTRACT
Background and Objective: Cholangiocarcinoma (CHCA) is the most common cancer in Thai people especially in the Northeast of Thailand. Primary prevention is very important for CHCA control. This study attempted to find the exposures associate with CHCA in order to develop a predictive statistical model for CHCA in people in Northeast Thailand.Methods: This study was carried out in 2007 as a nested case-control study within the Khon Kaen cohort study at Cancer Unit, Khon Kaen University. The cohort recruitment was performed during 1990 to 2001. There were 108 CHCA cases occurred in the cohort and individual matched control was randomly selected for each case (1:1), matched by age, sex and date of recruitment to the cohort.Results: For the predictive model, was: logit (CHCA) = 0.69 X Opisthorchis Viverrini, OV (egg in stool finding) with the precision of 56.48% (95%CI:= 51.25-61.71), sensitivity 54.02% (95%CI: = 46.32 - 61.59), specificity 66.67% (95%CI: = 50.45 - 80.43), positive predictive value 87.04% (95%CI:=79.21-92.73) and negative predictive value 25.93% (95%CI:=17.97-5.25).Conclusion: The results of this study suggested that OV infestation has high association with CHCA. To reduce the incidence of CHCA, liver fluke control is priority work for health policy.Keywords: Cholangiocarcinoma, Risk factors for cholangiocarcinoma, Predictive model for cholangiocarcinoma